Our Labs

Acharya Lab

The Acharya lab studies how immune cells integrate signals from pathogens and their environment to produce effective immunity against pathogens while maintaining tolerance to self-derived antigens.
Allenspach Lab

The Allenspach Lab focuses on translational work to understand immune dysregulation disorders - those with overlapping immunodeficiency and autoimmune features.
Jackson Lab

The Jackson Lab studies the immune mechanisms underlying the development of systemic autoimmune diseases, focusing in particular on the role of B cells in systemic lupus erythematosus (SLE). The lab uses various chimeric and genetic knock-in murine strains to model the biology of human autoimmune diseases.
James Lab

The James Lab is interested in uncovering biochemical mechanisms that contribute to drug resistance and to immunological disease. To do so, we investigate many features of protein behavior, including their impact on differentiation, their interactions with other molecules and whether mutation regulates these processes.

Related topics: Immunology, B cells, genetic variation
Miao Lab

The Miao Lab is pursuing safer, more effective treatments for hemophilia. Our current work focuses on innovative gene therapy approaches.
Mohammadi Lab

We are interested in the design of probabilistic machine learning methods and statistical models that incorporate known biochemical principles to facilitate decision-making from limited data and to allow for asking smarter questions. We have a major focus on quantitative analysis of regulatory variation inthe human genome from large scale functional genomics data and its application to rare diseases and precision medicine.
Piliponsky Lab

The Piliponsky Lab studies inflammatory responses involving mast cells and myeloid cells. Our goal is to understand how the body controls the immune system’s response to bacterial infections – and how this process becomes dysregulated.
Torbett Lab

The Torbett Lab studies HIV entry, evolution, and assembly at the genomic, biochemical and structural levels, as well as human hematopoietic stem cell resistance of HIV lentiviral vector entry.

Center for Immunity and Immunotherapies

For questions or inquiries,
email: ciitadmin@seattlechildrens.org.

Physical Address

1920 Terry Ave.
Seattle, WA 98101

Mailing Address

PO Box 5371
Seattle, WA 98145-5005

Seattle Children’s complies with applicable federal and other civil rights laws and does not discriminate, exclude people or treat them differently based on race, color, religion (creed), sex, gender identity or expression, sexual orientation, national origin (ancestry), age, disability, or any other status protected by applicable federal, state or local law. Financial assistance for medically necessary services is based on family income and hospital resources and is provided to children under age 21 whose primary residence is in Washington, Alaska, Montana or Idaho.